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James G Christensen Selected Research

Lymphoma (Lymphomas)

4/2008An in vivo model of Met-driven lymphoma as a tool to explore the therapeutic potential of Met inhibitors.
12/2007Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.

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James G Christensen Research Topics

Disease

92Neoplasms (Cancer)
04/2024 - 01/2003
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2024 - 02/2005
9Lung Neoplasms (Lung Cancer)
02/2024 - 05/2008
9Neoplasm Metastasis (Metastasis)
10/2023 - 03/2009
6Colorectal Neoplasms (Colorectal Cancer)
04/2024 - 02/2011
5Adenocarcinoma
02/2024 - 02/2005
5Breast Neoplasms (Breast Cancer)
01/2018 - 03/2009
5Glioblastoma (Glioblastoma Multiforme)
04/2012 - 06/2005
5Stomach Neoplasms (Stomach Cancer)
03/2012 - 02/2006
4Carcinoma (Carcinomatosis)
01/2019 - 06/2005
4Neuroblastoma
11/2011 - 05/2008
3Fatigue
02/2024 - 04/2013
3Diarrhea
02/2024 - 04/2013
3Colonic Neoplasms (Colon Cancer)
01/2020 - 07/2011
3Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
03/2012 - 12/2007
2Nausea
02/2024 - 01/2023
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2024 - 06/2005
2Triple Negative Breast Neoplasms
01/2018 - 03/2013
2Melanoma (Melanoma, Malignant)
07/2014 - 03/2009
2Ovarian Neoplasms (Ovarian Cancer)
12/2013 - 01/2010
2Retinoblastoma (Glioblastoma, Retinal)
08/2013 - 03/2012
2Renal Cell Carcinoma (Grawitz Tumor)
08/2013 - 05/2006
2Adenocarcinoma of Lung
06/2013 - 08/2012
2Neuroendocrine Tumors (Neuroendocrine Tumor)
06/2013 - 03/2012
2Disease Progression
04/2013 - 05/2006
2Genetic Translocation (Chromosomal Translocation)
05/2008 - 12/2007
2Lymphoma (Lymphomas)
04/2008 - 12/2007
1Vomiting
01/2023

Drug/Important Bio-Agent (IBA)

26CrizotinibIBA
01/2020 - 05/2007
23Phosphotransferases (Kinase)IBA
01/2015 - 09/2003
14Proteins (Proteins, Gene)FDA Link
04/2024 - 07/2005
13adagrasibIBA
04/2024 - 01/2020
12Tyrosine Kinase InhibitorsIBA
01/2019 - 10/2004
12Sunitinib (Sutent)FDA Link
06/2013 - 01/2003
11Anaplastic Lymphoma KinaseIBA
01/2015 - 12/2007
11Proto-Oncogene Proteins c-metIBA
07/2012 - 09/2003
10Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
06/2013 - 11/2003
9Biomarkers (Surrogate Marker)IBA
02/2024 - 06/2005
9ErbB Receptors (EGF Receptor)IBA
10/2012 - 06/2005
95- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA
02/2011 - 11/2003
6LigandsIBA
01/2022 - 11/2003
6Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
11/2014 - 07/2005
6Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2011 - 09/2003
42- amino- 8- (4- (2- hydroxyethoxy)cyclohexyl)- 6- (6- methoxypyridin- 3- yl)- 4- methylpyrido(2,3- d)pyrimidin- 7(8H)- oneIBA
11/2014 - 11/2011
4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2013 - 11/2008
42- (4- (3- quinolin- 6- ylmethyl- 3H- (1,2,3)triazolo(4,5- b)pyrazin- 5- yl)pyrazol- 1- yl)ethanolIBA
06/2013 - 01/2012
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 06/2005
3Alanine Transaminase (SGPT)IBA
02/2024 - 01/2020
3glesatinibIBA
02/2024 - 11/2017
3Pemetrexed (MTA)FDA Link
11/2023 - 10/2022
3KRASG12D inhibitor MRTX1133IBA
01/2023 - 01/2022
3Tyrosine (L-Tyrosine)FDA Link
01/2018 - 06/2005
3dacomitinibIBA
11/2014 - 02/2012
3Docetaxel (Taxotere)FDA Link
03/2013 - 07/2009
3Lapatinib (GW572016)FDA Link
09/2012 - 02/2012
3Trastuzumab (Herceptin)FDA Link
09/2012 - 07/2005
3Angiogenesis InhibitorsIBA
07/2012 - 10/2007
3tyrosine receptor (receptor, tyrosine)IBA
04/2012 - 05/2006
3Gefitinib (Iressa)FDA Link
02/2012 - 07/2005
3((3Z)- N- (3- chlorophenyl)- 3- ((3,5- dimethyl- 4- ((4- methylpiperazin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- N- methyl- 2- oxo- 2,3- dihydro- 1H- indole- 5- sulfonamide)IBA
04/2009 - 09/2003
2SuspensionsIBA
02/2024 - 01/2023
2TabletsIBA
02/2024 - 01/2023
2Capsules (Microcapsules)IBA
02/2024 - 01/2023
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2024 - 01/2023
2sotorasibIBA
02/2024 - 01/2021
2Cetuximab (Erbitux)FDA Link
01/2023 - 02/2011
2SaltsIBA
01/2023 - 06/2005
2PlatinumIBA
01/2022 - 12/2013
2Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2021 - 06/2013
2Codon (Codons)IBA
01/2021 - 06/2013
2Histone Deacetylases (Histone Deacetylase)IBA
01/2019 - 01/2018
2mocetinostatIBA
01/2019 - 01/2018
2Erlotinib Hydrochloride (CP 358,774)FDA Link
10/2016 - 11/2011
2Sirolimus (Rapamycin)FDA Link
11/2014 - 03/2005
2palbociclibIBA
07/2014 - 08/2013
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
12/2013 - 02/2012
2Insulin-Like PeptidesIBA
12/2013 - 03/2012
2figitumumabIBA
12/2013 - 07/2011
2mirdametinibIBA
12/2013 - 08/2012
2nirogacestatIBA
03/2013 - 09/2012
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
03/2013 - 09/2012
2AfatinibIBA
10/2012 - 02/2012
2Messenger RNA (mRNA)IBA
09/2012 - 06/2005
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
04/2012 - 04/2012
2Small Interfering RNA (siRNA)IBA
04/2012 - 02/2005
2N- (2- (6- (4- cyclobutylamino- 5- trifluoromethylpyrimidine- 2- ylamino)- 1,2,3,4- tetrahydro- 1,4- epiazano- naphthalen- 9- yl)- 2- oxo- ethyl)acetamideIBA
03/2012 - 04/2010
2Canertinib (CI 1033)IBA
02/2012 - 06/2005
2Phosphatidylinositols (Phosphatidylinositol)IBA
11/2011 - 11/2008
2Adenosine Triphosphate (ATP)IBA
08/2011 - 11/2003
2Semaphorins (Semaphorin)IBA
04/2009 - 02/2005
2Growth Factor ReceptorsIBA
11/2008 - 02/2006
2Mesylates (Mesylate)IBA
05/2006 - 06/2005
2Imatinib Mesylate (Gleevec)FDA Link
05/2006 - 07/2005
1NucleotidesIBA
04/2024
1SOS1 ProteinIBA
04/2024
1Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA
11/2023
1glycolic acid (glycolate)IBA
01/2023

Therapy/Procedure

41Therapeutics
04/2024 - 01/2003
4Oral Administration
10/2022 - 06/2005
4Drug Therapy (Chemotherapy)
01/2022 - 02/2012